Motif ID: RXRA_VDR{dimer}.p2

Z-value: 1.253


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VDRchr12_-_482987650.161.6e-02Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_39899749 37.939


chr19_-_36399205 31.901 NM_001173514
NM_001173515
NM_003332
NM_198125
TYROBP



TYRO protein tyrosine kinase binding protein



chr19_-_36399120 31.204 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_-_36399183 28.009 TYROBP
TYRO protein tyrosine kinase binding protein
chr2_+_230787195 18.650 NM_174899
FBXO36
F-box protein 36
chr12_-_6579754 17.854 NM_014231
NM_016830
NM_199245
VAMP1


vesicle-associated membrane protein 1 (synaptobrevin 1)


chr19_+_56186426 17.216 NM_001130072
NM_013333
EPN1

epsin 1

chr19_+_1941184 17.161 CSNK1G2
casein kinase 1, gamma 2
chr17_+_2699731 16.705 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr21_-_46340821 15.417 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_64863700 13.807 C11orf2
chromosome 11 open reading frame 2
chr11_+_64863711 13.725 C11orf2
chromosome 11 open reading frame 2
chr11_+_64863607 13.685 NM_013265
C11orf2
chromosome 11 open reading frame 2
chr18_-_6414900 13.598 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr20_+_3801164 13.247 NM_001204446
NM_001204447
NM_018347
C20orf29


chromosome 20 open reading frame 29


chr19_+_56186569 12.563 EPN1
epsin 1
chr17_+_36283959 12.428 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_-_34503914 12.318 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr17_-_36348585 12.272 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr17_-_34756980 12.246 NM_001123392
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
3.94 3.62e-02 GO:0030811 regulation of nucleotide catabolic process
3.94 3.62e-02 GO:0033121 regulation of purine nucleotide catabolic process
3.05 2.34e-02 GO:0009894 regulation of catabolic process
2.99 2.59e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.84 1.56e-02 GO:0007409 axonogenesis
2.82 1.14e-02 GO:0048812 neuron projection morphogenesis
2.81 3.07e-03 GO:0032990 cell part morphogenesis
2.77 6.02e-03 GO:0031175 neuron projection development
2.73 8.19e-03 GO:0048858 cell projection morphogenesis
2.71 6.83e-04 GO:0032989 cellular component morphogenesis
2.63 2.21e-02 GO:0000904 cell morphogenesis involved in differentiation
2.58 6.34e-03 GO:0000902 cell morphogenesis
2.50 7.83e-03 GO:0030030 cell projection organization
2.49 2.60e-02 GO:0048666 neuron development
1.71 4.35e-02 GO:0048583 regulation of response to stimulus
1.33 1.08e-03 GO:0050789 regulation of biological process
1.32 7.50e-04 GO:0065007 biological regulation
1.29 3.85e-02 GO:0050794 regulation of cellular process
1.20 1.28e-03 GO:0009987 cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
8.69 4.29e-03 GO:0003823 antigen binding
6.82 2.20e-02 GO:0005097 Rab GTPase activator activity